| Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation |
Jiaowei Wang,Wenguang Xie,Nan Li,Wenjuan Li,Zhishuai Zhang,Nana Fan,Zhen Ouyang,Yu Zhao,Chengdan Lai,Hao Li,Mengqi Chen,Longquan Quan,Yunpan Li,Yu Jiang,Wenqi Jia,Lixin Fu,Md. Abdul Mazid, Yanling Zhu,Patrick H. Maxwel,Guangjin Pan,Miguel A. Esteban,Zhen Dai,Liangxue Lai |
2023 |
Cell Stem Cell |
| Nuclear localization of TET2 requires β-catenin activation and correlates with favourable prognosis in colorectal cancer |
Changpeng Li,Jingcai He,Fei Meng,Fuhui Wang,Hao Sun,Huizhong Zhang,Linna Dong,Mengdan Zhang,Qiaoran Xu,Lining Liang,Yuan Li,Tingting Yang,Meiai He,Tao Wang,Jiechun Lin,Jiaqi Sun,Qiuling Huang, Lin Guo,Xiaofei Zhang,Shijuan Mai,Hui Zheng |
2023 |
Cell Death & Disease |
| Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte |
Shiting Zhao,Tao Nie,Lei Li,Qiaoyun Long,Ping Gu,Yuwei Zhang,Wei Sun,Zexin Lin,Qing Liu,Yue Qi,Wei Wang,Mengyuan Xie,Kerry Loomes,Chenleng Cai,Donghai Wu,Hannah Xiaoyan Hui |
2023 |
Advanced Science |
| 1-Benzyloxy-5-phenyltetrazole derivatives highly active against androgen receptor-dependent prostate cancer cells |
Shiting Zhao,Abdelsalam S Ali,Xinyu Kong,Yan Zhang,Xiaomin Liu,Melissa A Skidmore,Craig M Forsyth,G Paul Savage,Donghai Wu,Yong Xu,Craig L Francis |
2023 |
European Journal of Medicinal Chemistry |
| DEP2: an upgraded comprehensive analysis toolkit for quantitative proteomics data |
Zhenhuan Feng,Peiyang Fang,Hui Zheng,Xiaofei Zhang |
2023 |
Bioinformatics |
| MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy |
Xue Shi, Wenfeng Wu, Zhenhuan Feng, Peiyang Fan, Ruona Shi, Xiaofei Zhang |
2023 |
Cell Reports |
| SARS-CoV-2 induces cardiomyocyte apoptosis and inflammation but can be ameliorated by ACE inhibitor Captopril |
Xiaohan Huang,Wenxia Fan,Jing Sun,Jiaqing Yang,Yanjun Zhang,Qian Wang？Pingchao Li,Yudi Zhang,Shengnan Zhang,Heying Li,Jianhua Wang,Liqiang Feng,Jincun Zhao,Ling Chen,Linbing Qu |
2023 |
Antiviral Research |
| Rational Design, Synthesis and Biological Evaluation of Benzo[d]isoxazole Derivatives as Potent BET Bivalent Inhibitors for Potential Treatment of Prostate Cancer |
Junhua Li, Run Zhu, Xiaoxi Zhuang, Cheng Zhang, Hui Shen, Xishan Wu, Maofeng Zhang, Cen Huang, Qiuping Xiang, Linxiang Zhao, Yong Xu, Yan Zhang |
2023 |
Bioorganic Chemistry |
| BRPF1 bridges H3K4me3 and H3K23ac in human embryonic stem cells and is essential to pluripotency |
Cong Zhang, Huaisong Lin, Yanqi Zhang, Qi Xing, Jingyuan Zhang, Di Zhang, Yancai Liu, Qianyu Chen, Tiancheng Zhou, Junwei Wang, Yongli Shan, Guangjin Pan |
2023 |
iScience |
| Comparative genome analysis reveals high-level drug resistance markers in a clinical isolate of Mycobacterium fortuitum subsp. fortuitum MF GZ001 |
Md Shah Alam, Ping Guan, Yuting Zhu, Sanshan Zeng, Xiange Fang, Shuai Wang, Buhari Yusuf, Jingran Zhang, Xirong Tian, Cuiting Fang, Yamin Gao, Mst Sumaia Khatun, Zhiyong Liu, H. M. Adnan Hameed, Yaoju Tan, Jinxing Hu, Jianxiong Liu, Tianyu Zhang |
2023 |
Frontiers in Cellular and Infection Microbiology |
| Inherently Chiral 6,7-Diphenyldibenzo[e,g][1,4]diazocine: Enantioselective Synthesis and Application as a Ligand Platform |
Yu Luo, Xilong Wang, Weiming Hu, Yan Peng, Chaoqin Wang, Ting Yu, Sidi Cheng, Jing Li, Yimiao He, Chunfang Gan, Shuang Luo,Qiang Zhu |
2023 |
CCS Chemistry |
| Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques |
Li, Pingchao; Wang, Qian; He, Yizi; Yang, Chenchen; Zhang, Zhengyuan; Liu, Zijian; Liu, Bo; Yin, Li; Cui, Yilan; Hu, Peiyu; Liu, Yichu; Zheng, Pingqian; Wang, Wei; Qu, Linbing; Sun, Caijun; Guan, Suhua; Feng, Liqiang; Chen, Ling |
2023 |
EMERGING MICROBES & INFECTIONS |
| Low glutaminase and glycolysis correlate with a high transdifferentiation efficiency in mouse cortex |
Li, Yuan; Yang, Tingting; Cheng, Yingying; Hou, Jinfei; Liu, Zhaoming; Zhao, Yu; Chen, Shiyu; Qin, Zhaohui; Wang, Chenchen; Song, Weining; Ge, Haofei; Li, Changpeng; Liang, Lining; Guo, Lin; Sun, Hao; Wu, Lin-Ping; Zheng, Hui |
2023 |
CELL PROLIFERATION |
| Antigen-specific TCR-T cells from Rag2 gene-deleted pluripotent stem cells impede solid tumour growth in a mouse model |
Wu, Bingyan; Zhang, Qi; Hong, Pingshan; Liu, Lijuan; Peng, Huan; Xia, Chengxiang; Wang, Tongjie; Wang, Yao; Weng, Qitong; Liu, Xiaofei; Geng, Yang; Wang, Jinyong; Wu, Hongling |
2023 |
CELL PROLIFERATION |
| Harnessing enhanced CRISPR/Cas12a trans-cleavage activity with extended reporters and reductants for early diagnosis of Helicobacter pylori, the causative agent of peptic ulcers and stomach cancer |
Habimana, Jean de Dieu; Mukama, Omar; Chen, Guiquan; Chen, Mengjun; Amissah, Obed Boadi; Wang, Lin; Liu, Yujie; Sun, Yirong; Li, Amy L.; Deng, Sihao; Huang, Jufang; Yan, Xiao-xin; Rutaganda, Theobard; Mutangana, Dieudonne; Wu, Lin-Ping; Huang, Rongqi; Li, Zhiyuan |
2023 |
BIOSENSORS & BIOELECTRONICS |
| Palladium-catalyzed alkyne hydrocarbonylation under atmospheric pressure of carbon monoxide in the presence of hydrosilane |
Luo, Yu; Wang, Xilong; Liu, Qianwen; He, Yimiao; Li, Jing; Luo, Shuang; Zhu, Qiang |
2023 |
GREEN CHEMISTRY |
| Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation |
Jin, Qin; Liu, Xiaoyi; Zhuang, Zhenpeng; Huang, Jiayuan; Gou, Shixue; Shi, Hui; Zhao, Yu; Ouyang, Zhen; Liu, Zhaoming; Li, Lei; Mao, Junjie; Ge, Weikai; Chen, Fangbing; Yu, Manya; Guan, Yezhi; Ye, Yinghua; Tang, Chengcheng; Huang, Ren; Wang, Kepin; Lai, Liangxue |
2023 |
GENOME BIOLOGY |
| Prolonged generation of multi-lineage blood cells in wild type animals from pluripotent stem cells |
Huan Peng , Yunqing Lin , Fangxiao Hu , Cui Lv , Bingyan Wu , Qitong Weng , Lijuan Liu , Chengxiang Xia , Xiaofei Liu , Yalan Zhao , Qi Zhang , Yang Geng , Mengyun Zhang , Jinyong Wang |
2023 |
Stem Cell Reports |
| Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer |
Qiuping Xiang, Chao Wang, Tianbang Wu, Cheng Zhang, Qingqing Hu, Guolong Luo, Jiankang Hu , Xiaoxi Zhuang, Lingjiao Zou , Hui Shen, Xishan Wu , Yan Zhang , Xiangqian Kong, Jinsong Liu, Yong Xu |
2022 |
Journal of Medicinal Chemistry |
| Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants |
Qihong Yan , Ruitian Hou , Xiaohan Huang , Yanjun Zhang , Ping He , Yudi Zhang , Banghui Liu , Qian Wang , Haiyue Rao , Xianying Chen , Xinwei Zhao , Xuefeng Niu , Jincun Zhao , Xiaoli Xiong , Ling Chen |
2022 |
Emerging Microbes & Infections |
| Origin and Reversion of Omicron Core Mutations in the Evolution of SARS-CoV-2 Genomes |
Xin-Wei Zhao, Luyao Qin, Xiao Ding, Yudi Zhang, Xuefeng Niu, Feng Gao , Taijiao Jiang
and Ling Chen. |
2022 |
Viruses |
| Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1- ones as novel selective TRIM24/BRPF1 bromodomain inhibitors |
Qiuping Xiang,Guolong Luo,Cheng Zhang,Qingqing Hua,Chao Wang,Tianbang Wu,c,Hongrui Xu,Jiankan gHu,Xiaoxi Zhuang,Maofeng Zhang,Shuang Wu,Jinxin Xu,YanZhang,Jinsong Liu,Yong Xu |
2022 |
European Journal of Medicinal Chemistry |
| Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation |
Wei Li, Qi Long , Hao Wu, Yanshuang Zhou , Lifan Duan, Hao Yuan , Yingzhe Ding , Yile Huang , Yi Wu , Jinyu Huang, Delong Liu, Baodan Chen, Jian Zhang , Juntao Qi, Shiwei Du, Linpeng Li , Yang Liu, Zifeng Ruan, Zihuang Liu, Zichao Liu, Yifan Zhao , Jianghuan Lu, Junwei Wang, Wai-Yee Chan & Xingguo Liu. |
2022 |
Nature Communications |
| Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXRα heterodimer |
Mohan Zhao,Na Wang,Yaoting Guo,Jingwen Li,Yue Yin,Yan Dong,Jiabin Zhu,Chao Peng,Tingting Xu,Jinsong Liu |
2022 |
Proceedings of the National Academy of Sciences of the United States of America |
| YY1 safeguard multidimensional epigenetic landscape associated with extended pluripotency |
Xiaotao Dong,？Rong Guo,？Tianrong Ji,？Jie Zhang,？Jun Xu,？Yaoyi Li,？Yingliang Sheng,？Yuxiang Wang,？Ke Fang,？Yulin Wen,？Bei Liu,？Gongcheng Hu,？Hongkui Deng,？Hongjie Yao |
2022 |
Nucleic Acids Research |
| Identification of a group of bisbenzylisoquinoline (BBIQ) compounds as ferroptosis inhibitors |
Yipu Fan, Yihan Zhang, Kunyu Shi, Shan Cheng, Duanqing Pei and Xiaodong Shu |
2022 |
Cell Death＆Disease |
| From immune equilibrium to immunodynamics |
Xiaoping Chen |
2022 |
Frontiers in Microbiology |
| Parallel Kinetic Resolution through Palladium-Catalyzed Enantioselective Cycloimidoylation: En Route to Divergent N-Heterocycles Bearing a Quaternary Stereogenic Center |
Xilong Wang, Yu Luo, Jing Li, Chaoqin Wang, Qianwen Liu, Yimiao He, Shuang Luo* and Qiang Zhu |
2022 |
ACS Catalysis |
| Hepatic DKK1-driven steatosis is CD36 dependent |
Zhen Yang？,？Xinping Huang,？Jiaye Zhang,？Kai You,？Yue Xiong,？Ji Fang,？Anteneh Getachew,？Ziqi Cheng,？Xiaorui Yu,？Yan Wang,？Feima Wu,？Ning Wang,？Shufen Feng,？Xianhua Lin,？Fan Yang,？Yan Chen,？Hongcheng Wei,？Yin-Xiong Li |
2022 |
LIFE SCIENCE ALLIANCE |
| Harnessing enhanced CRISPR/Cas12a trans-cleavage activity with
extended reporters and reductants for early diagnosis of Helicobacter pylori,
the causative agent of peptic ulcers and stomach cancer |
Jean de Dieu Habimana, Omar Mukama, Guiquan Chen, Mengjun Chen, Obed
Boadi Amissah, Lin Wang, Yujie Liu, Yirong Sun, Amy L. Li, Sihao Deng,
Jufang Huang, Xiao-xin Yan, Theobard Rutaganda, Dieudonne Mutangana, Lin-Ping Wu,
Rongqi Huang ,Zhiyuan Li |
2022 |
Biosensors and Bioelectronics |
